Overlord is amazing, but definitely a very different vibe from Apothecary Diaries, despite being in the same fantasy genre.

I think I would say this happened to me once when I went from watching Coffin Princess Chaika to Skeleton Knight in Another World.

Like your experience, Chaika and Skeleton Knight are both fantasy themed anime, but boy was the beginning of EP1 of Skeleton Knight uncomfortable. I mean, it was like that on purpose, and it obviously achieved what it was trying to accomplish, but I think that that type of opening would have been better if they showed a whole lot less than they did (which was still basically nothing, by the way). Goblin Slayer had a shocking opening, but it gave a good reason to the viewer why goblins would be hated, and made goblins a justifiably evil villain for the show. Skeleton Knight on the other hand, could probably have gone without the opening and would have been fine as the rest of the show doesn’t ever really match that intensity.

Chaika was a mostly fun show, with an easy to follow plot. Skeleton Knight, while also easy to follow and a mostly fun plot, had massive whiplash from its opening episode, at least IMO. I am not a thin-skinned person, and while I don’t necessarily feel good or comfortable with certain onscreen actions, I do think that they can be used to enhance a story, depending on context and presentation. But in Skeleton Knight, it didnt really add anything, it just left me wondering for the rest of the entire show “why did they chcoose to open the show like that, was that a shock style marketing attempt?”