Lucky Star and K-on for CGDCT

Evangelion for meta-commentary and deconstruction, to the point that future works that qualify often get called the “Evangelion of <genre>”

Fullmetal Alchemist Brotherhood and Attack on Titan for battle shounen

Bocchi the Rock for girls band anime, specifically

Lupin III: The Castle of Cagliostro for pretty much all of Ghibli

Akira for 90s anime